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Product Description
anti- ERCC6 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex(DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions..
Immunogen: excision repair cross-complementing rodent repair deficiency, complementation group 6
Synonyms: CSB
Reactivity: Human
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab02836(ERCC6/CSB antibody) at dilution of 1:500
Gene ID: 2074
Research Area: Metabolism
Uniprot ID: Q03468
