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Product Description
anti- ERLIN2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation(ERAD) of inositol 1,4,5-trisphosphate receptors(IP3Rs) such as ITPR1(PubMed:19240031, PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex(PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex(PubMed:24217618)..
Immunogen: ER lipid raft associated 2
Synonyms: C8orf2, SPFH2
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab02849(ERLIN2 antibody) at dilution of 1:500
Gene ID: 11160
Research Area: Metabolism
Uniprot ID: O94905
