Product Description
anti- FADD antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas(CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex(DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling..
Immunogen: Fas(TNFRSF6)-associated via death domain
Synonyms: FADD, GIG3, MORT1, Protein FADD
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, IHC, WB, IP
Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP: 1:50 - 1:200
Image 1: Immunohistochemistry of paraffin-embedded human lung cancer using FNab02941(FADD antibody) at dilution of 1:50
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Image 4: Hela cells were subjected to SDS PAGE followed by western blot with FNab02941(FADD Antibody) at dilution of 1:1000
Gene ID: 8772
Research Area: Metabolism
Uniprot ID: Q13158