anti- FAM175A antibody

Product Description

anti- FAM175A antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Involved in DNA damage response and double-strand break(DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX..

Immunogen: family with sequence similarity 175, member A

Synonyms: ABRA1, CCDC98

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500-1:2400; IHC: 1:20-1:200; IF: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer using FNab02974(FAM175A antibody) at dilution of 1:100

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Image 4: human testis tissue were subjected to SDS PAGE followed by western blot with FNab02974(FAM175A antibody) at dilution of 1:500

Gene ID: 84142

Research Area: Metabolism

Uniprot ID: Q6UWZ7