anti- FANCD2 antibody

Product Description

anti- FANCD2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.The antibody recognize both un-phospho and phospho-Ser(330) of FANCD2..

Immunogen: Fanconi anemia, complementation group D2

Synonyms: DKFZp762A223, FA D2, FA4, FACD, FAD, FAD2, FANCD, FANCD2, FLJ23826, Protein FACD2

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC, IP

Recommended dilution: WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human testis using FNab03006(FANCD2 antibody) at dilution of 1:50

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Image 4: HL-60 cells were subjected to SDS PAGE followed by western blot with FNab03006(FANCD2 antibody) at dilution of 1:500

Gene ID: 2177

Research Area: Metabolism

Uniprot ID: Q9BXW9