anti- FAS/CD95 antibody

Product Description

anti- FAS/CD95 antibody is available at Gentaur for Next week Delivery.

Purification: Protein A+G purification

Background: Fas(CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor(TNF) receptor superfamily. It can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex(DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form(40-55 kDa) of Fas is due to glycosylation..

Immunogen: Fas(TNF receptor superfamily, member 6)

Synonyms: ALPS1A, APO 1, Apo 1 antigen, APT1, CD95, FAS, FAS1, FASLG receptor, FASTM, TNFRSF6

Reactivity: Human, Mouse

Tested Application: ELISA, WB, FC,IHC

Recommended dilution: WB: 1:1000-1:8000; IHC: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab03017(FAS/CD95 antibody) at dilution of 1:200.

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab03017(FAS/CD95 antibody) at dilution of 1:4000

Gene ID: 355

Research Area: Metabolism

Uniprot ID: P25445