anti- FBXO2 antibody

Product Description

anti- FBXO2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway(ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type(By similarity)..

Immunogen: F-box protein 2

Synonyms: FBX2

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, WB

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human brain using FNab03040(FBXO2 antibody) at dilution of 1:50

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Image 4: SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab03040(FBXO2 Antibody) at dilution of 1:300

Gene ID: 26232

Research Area: Metabolism

Uniprot ID: Q9UK22