Product Description
anti- FHIT antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: This gene, a member of the histidine triad gene family, encodes a diadenosine 5', 5'''-P1, P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene..
Immunogen: FHIT
Synonyms: AP3Aase, FRA3B
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Image 1: Immunohistochemistry of paraffin-embedded mouse heart tissue slide using FNab09817( FHIT antibody) at dilution of 1:200
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab09817 at dilution of 1:1000
Gene ID: 2272
Research Area: Metabolism
Uniprot ID: P49789