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Product Description
anti- FRS2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1..
Immunogen: fibroblast growth factor receptor substrate 2
Synonyms: FGFR signaling adaptor SNT, FGFR substrate 2, FRS2, FRS2A, FRS2alpha, SNT, SNT 1, SNT1
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, IHC, WB, IF
Recommended dilution: WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100
Image 1: Immunohistochemistry of paraffin-embedded human prostate cancer using FNab03225(FRS2 antibody) at dilution of 1:50
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Image 4: MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab03225(FRS2 Antibody) at dilution of 1:1000
Gene ID: 10818
Research Area: Metabolism
Uniprot ID: Q8WU20
