Product Description
anti- FXN antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: FXN, also named as FRDA, X25, m81-FXN, d-FXN, m78-FXN and i-FXN, belongs to the frataxin family. It promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. FXN may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. FXN is cleaved to be 4 chains. The mature form of FXN is 14 or 18kDa..
Immunogen: frataxin
Synonyms: CyaY, d FXN, FA, FARR, frataxin, Frataxin(81 210), Frataxin, mitochondrial, FRDA, Friedreich ataxia protein, FXN, i FXN Frataxin(56 210), m56 FXN Frataxin(78 210), m78 FXN Frataxin mature form, m81 FXN, X25
Reactivity: Human
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: K562 cells were subjected to SDS PAGE followed by western blot with FNab03255(FXN antibody) at dilution of 1:1000
Gene ID: 2395
Research Area: Metabolism
Uniprot ID: Q16595