Product Description
anti- GAD1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form..
Immunogen: glutamate decarboxylase 1
Synonyms: FLJ45882, GAD, GAD 67, GAD1, GAD67, Glutamate decarboxylase 1, SCP
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution: WB: 1:500 - 1:2000
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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09843( GAD1 Antibody) at dilution of 1:1000
Gene ID: 2571
Research Area: Metabolism
Uniprot ID: Q99259