anti- GHRL antibody

Product Description

anti- GHRL antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression..

Immunogen: ghrelin/obestatin prepropeptide

Synonyms: MTLRP

Reactivity: Human, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human stomach using FNab03452(GHRL antibody) at dilution of 1:100

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Image 4: human stomach tissue were subjected to SDS PAGE followed by western blot with FNab03452(GHRL antibody) at dilution of 1:1000

Gene ID: 51738

Research Area: Metabolism

Uniprot ID: Q9UBU3