Product Description
anti- GLRX2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione(GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release..
Immunogen: glutaredoxin 2
Synonyms: GRX2
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: A549 cells were subjected to SDS PAGE followed by western blot with FNab03491(GLRX2 antibody) at dilution of 1:200
Gene ID: 51022
Research Area: Metabolism
Uniprot ID: Q9NS18