Product Description
anti- GNE antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms..
Immunogen: glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
Synonyms: GLCNE
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Image 1: Immunohistochemistry of paraffin-embedded human stomach using FNab03544(GNE Antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab03544(GNE Antibody) at dilution of 1:1000
Gene ID: 10020
Research Area: Metabolism
Uniprot ID: Q9Y223