anti- GPR177 antibody

Product Description

anti- GPR177 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: GPR177, also known as Wntless (WLS) or Evi, is an evolutionarily conserved transmembrane protein necessary for Wnt protein secretion. GPR177 localizes to compartments of the secretory pathway, including the ER, Golgi apparatus, endosomes, and plasma membrane. GPR177 is overexpressed in several cancer types including glioma and gastric cancer. Several isoforms of GPR177 exist due to the alternative splicing, with predicted MW around 62 and 51 kDa, respectively. The sequence can be processed by removing the signal peptide, which generates a mature form of 45-46 kDa. In addition, slow migragrating band above 62 kDa can also be detected because GPR177 is modified by N-linked glycosylation (PMID: 20549736)..

Immunogen: G protein-coupled receptor 177

Synonyms: C1orf139, EVI, G protein coupled receptor 177, GPR177, Protein wntless homolog, Sprinter, WLS, Wntless

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IP

Recommended dilution: WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human ovary using FNab03601(GPR177 antibody) at dilution of 1:100

Image 2: .

Image 3: IP Result of anti-GPR177 (IP: FNab03601, 3ug; Detection: FNab03601 1:500) with mouse liver tissue lysate 10000ug.

Image 4: mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab03601(GPR177 antibody) at dilution of 1:500

Gene ID: 79971

Research Area: Metabolism

Uniprot ID: Q5T9L3