Product Description
anti- GRB14 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor(INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal..
Immunogen: growth factor receptor-bound protein 14
Synonyms:
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, IHC, WB
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human ovary tumor using FNab03641(GRB14 antibody) at dilution of 1:50
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Image 4: DU 145 cells were subjected to SDS PAGE followed by western blot with FNab03641(GRB14 Antibody) at dilution of 1:600
Gene ID: 2888
Research Area: Metabolism
Uniprot ID: Q14449