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Product Description
anti- GRB7 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress(By similarity)..
Immunogen: growth factor receptor-bound protein 7
Synonyms:
Reactivity: Human, Mouse
Tested Application: ELISA, WB, IP
Recommended dilution:
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Image 4: A431 cells were subjected to SDS PAGE followed by western blot with FNab03643(GRB7 antibody) at dilution of 1:1000
Gene ID: 2886
Research Area: Metabolism
Uniprot ID: Q14451
