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Product Description
anti- GZMB antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases(aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3,-7,-9 and 10 to give rise to active enzymes mediating apoptosis..
Immunogen: granzyme B
Synonyms: CCPI, CGL 1, CGL1, CSP B, CSPB, CTLA1, CTSGL1, Endogenous granzyme B, Granzyme B, GZMB, HLP, SECT
Reactivity: Human
Tested Application: ELISA, WB, IHC, IF
Recommended dilution: WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500
Image 1: Immunohistochemistry of paraffin-embedded human lymphoma using FNab03737(GZMB antibody) at dilution of 1:100
Image 2: .
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Image 4: HL-60 cells were subjected to SDS PAGE followed by western blot with FNab03737(GZMB antibody) at dilution of 1:500
Gene ID: 3002
Research Area: Metabolism
Uniprot ID: P10144
