Product Description
anti- HDAC3 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene..
Immunogen: histone deacetylase 3
Synonyms: HD3
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, IHC, IP, WB, IF
Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:200; IP: 1:50 - 1:200; ChIP: 1:20 - 1:100
Image 1: Immunohistochemistry of paraffin-embedded human esophagus using FNab03798(HDAC3 antibody) at dilution of 1:100
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Image 4: HL-60 cells were subjected to SDS PAGE followed by western blot with FNab03798( HDAC3 Antibody) at dilution of 1:1000
Gene ID: 8841
Research Area: Metabolism
Uniprot ID: O15379