anti- Histone H2A.X antibody

Product Description

anti- Histone H2A.X antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif..

Immunogen: H2A histone family, member X

Synonyms: H2A histone family, member X, H2A.X, H2A/X, H2AFX, H2AX, Histone H2A.x

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:100 - 1:200; IF: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer using FNab03885(H2AFX antibody) at dilution of 1:100

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Image 4: HL-60 cells were subjected to SDS PAGE followed by western blot with FNab03885(H2AFX antibody) at dilution of 1:1000

Gene ID: 3014

Research Area: Metabolism

Uniprot ID: P16104