Product Description
anti- IDH1 antibody is available at Gentaur for Next week Delivery.
Purification: Protein A+G purification
Background: IDH1, also named as PICD and IDP, belongs to the isocitrate and isopropylmalate dehydrogenases family. It is a common feature of a major subset of primary human brain cancers. It can form a homodimer(PMID:15173171).IDH1 mutation is always heterozygotic and IDH1 functions as a dimer, theoretically there will be 25% each wild type and mutant homo-dimers and 50% hetero-dimers present in the tumor cells(PMID:21079649 )..
Immunogen: isocitrate dehydrogenase 1(NADP+), soluble
Synonyms: IDCD, IDH, IDH1, IDP, IDPC, NADP(+) specific ICDH, Oxalosuccinate decarboxylase, PICD
Reactivity: Human
Tested Application: ELISA, WB, IHC, IF
Recommended dilution: WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500
Image 1: Immunohistochemistry of paraffin-embedded human pancreas tissue slide using FNab04119(IDH1 Antibody) at dilution of 1:200
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Image 4: MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab04119(IDH1 Antibody) at dilution of 1:1000
Gene ID: 3417
Research Area: Metabolism
Uniprot ID: O75874