anti- IDO1 antibody

Product Description

anti- IDO1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway(PubMed:17671174). Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from uncontrolled and overreacting immune responses(PubMed:25691885). Tryptophan shortage inhibits T lymphocytes division and accumulation of tryptophan catabolites induces T-cell apoptosis and differentiation of regulatory T-cells(PubMed:25691885). Acts as a suppressor of anti-tumor immunity(PubMed:23103127, PubMed:25157255, PubMed:14502282, PubMed:25691885). Limits the growth of intracellular pathogens by depriving tryptophan(PubMed:25691885). Protects the fetus from maternal immune rejection(PubMed:25691885)..

Immunogen: indoleamine 2,3-dioxygenase 1

Synonyms: CD107B, IDO, IDO 1, IDO1, INDO, indoleamine 2,3 dioxygenase 1

Reactivity: Human, Rat

Tested Application: ELISA, IHC, WB

Recommended dilution: WB: 1:1000-1:4000; IHC: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab04127( IDO1 Antibody) at dilution of 1:100

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Image 4: Hela cells were subjected to SDS PAGE followed by western blot with FNab04127( IDO1 Antibody) at dilution of 1:2000

Gene ID: 3620

Research Area: Metabolism

Uniprot ID: P14902