anti- IL-6 antibody

Product Description

anti- IL-6 antibody is available at Gentaur for Next week Delivery.

Purification: Protein A+G purification

Background: Interleukin-6(IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity..

Immunogen: interleukin 6(interferon, beta 2)

Synonyms: B cell stimulatory factor 2, BSF 2, BSF2, CDF, CTL differentiation factor, HGF, HSF, Hybridoma growth factor, IFN beta 2, IFNB2, IL 6, IL6, IL-6, Interferon beta 2, Interleukin 6

Reactivity: Human, Rat

Tested Application: ELISA, IHC, WB

Recommended dilution: WB: 1:500-1:5000; IHC: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using FNab04283(IL6 Antibody) at dilution of 1:50

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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab04283(IL6 antibody) at dilution of 1:1000

Gene ID: 3569

Research Area: Metabolism

Uniprot ID: P05231