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Product Description
anti- IL10RA antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene..
Immunogen: interleukin 10 receptor, alpha
Synonyms: IL10R
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF
Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Image 1: Immunohistochemistry of paraffin-embedded rat brain using FNab04213(IL10RA Antibody) at dilution of 1:100
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Image 4: MCF7 cells were subjected to SDS PAGE followed by western blot with FNab04213(IL10RA antibody) at dilution of 1:1000
Gene ID: 3587
Research Area: Metabolism
Uniprot ID: Q13651
