Product Description
anti- IL17RC antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA(PubMed:16785495). Receptor for the heterodimer formed by IL17A and IL17B as part of a heterodimeric complex with IL17RA(PubMed:18684971). Has also been shown to be the cognate receptor for IL17F and to bind IL17A with high affinity without the need for IL17RA(PubMed:17911633). Activation of IL17RC leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1(PubMed:16785495). Isoform 5: Receptor for both IL17A and IL17F. Isoform 6: Does not bind IL17A or IL17F. Isoform 7: Does not bind IL17A or IL17F. Isoform 8: Receptor for both IL17A and IL17F..
Immunogen: interleukin 17 receptor C
Synonyms:
Reactivity: Human, Mouse
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with 1FNab04231(IL17RC antibody) at dilution of 1:200
Gene ID: 84818
Research Area: Metabolism
Uniprot ID: Q8NAC3