anti- ING3 antibody

Product Description

anti- ING3 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Component of the NuA4 histone acetyltransferase(HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome..

Immunogen: inhibitor of growth family, member 3

Synonyms:

Reactivity: Human, Mouse

Tested Application: ELISA, IHC, WB

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer using FNab04311(ING3 antibody) at dilution of 1:100

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Image 4: mouse uterus tissue were subjected to SDS PAGE followed by western blot with FNab04311(ING3 antibody) at dilution of 1:800

Gene ID: 54556

Research Area: Metabolism

Uniprot ID: Q9NXR8