anti- ING4 antibody

Product Description

anti- ING4 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor's(HIF) activity by interacting with HIF prolyl hydroxylase 2(EGLN1). Can enhance aopotosis induced by serum starvation in mammary epithelial cell line HC11(By similarity)..

Immunogen: inhibitor of growth family, member 4

Synonyms:

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IP

Recommended dilution:

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab04313(ING4 antibody) at dilution of 1:1500

Gene ID: 51147

Research Area: Metabolism

Uniprot ID: Q9UNL4