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Product Description
anti- INSIG2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins(SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR..
Immunogen: insulin induced gene 2
Synonyms:
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab04334(INSIG2 Antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: rat liver tissue were subjected to SDS PAGE followed by western blot with FNab04334(INSIG2 Antibody) at dilution of 1:1000
Gene ID: 51141
Research Area: Metabolism
Uniprot ID: Q9Y5U4
