anti- INSR antibody

Product Description

anti- INSR antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants..

Immunogen: insulin receptor

Synonyms: CD220

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded mouse liver using FNab04336(INSR antibody) at dilution of 1:50

Image 2: .

Image 3:

Image 4: mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab04336(INSR antibody) at dilution of 1:1000

Gene ID: 3643

Research Area: Metabolism

Uniprot ID: P06213