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Product Description
anti- IRF8 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes(the interferon consensus sequence(ICS)). Plays a negative regulatory role in cells of the immune system. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence(5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes(By similarity)..
Immunogen: interferon regulatory factor 8
Synonyms: ICSBP1
Reactivity: Human
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: Raji cells were subjected to SDS PAGE followed by western blot with FNab04396(IRF8 Antibody) at dilution of 1:1000
Gene ID: 3394
Research Area: Metabolism
Uniprot ID: Q02556
