anti- IST1 antibody

Product Description

anti- IST1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: ESCRT-III-like protein involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells(PubMed:19129479, PubMed:19129480). During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex: IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtubule severing(PubMed:26040712). Regulates early endosomal tubulation together with the ESCRT-III complex by mediating the recruitment of SPAST(PubMed:23897888)..

Immunogen: KIAA0174

Synonyms: KIAA0174

Reactivity: Human

Tested Application: ELISA, WB, IF, IHC, IP

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human lung cancer using FNab04408(hIST1 antibody) at dilution of 1:200

Image 2: .

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Image 4: human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab04408(hIST1 antibody) at dilution of 1:300

Gene ID: 9798

Research Area: Metabolism

Uniprot ID: P53990