anti- KHSRP antibody

Product Description

anti- KHSRP antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Binds to the dendritic targeting element and may play a role in mRNA trafficking(By similarity). Part of a ternary complex that binds to the downstream control sequence(DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element(FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements(AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs..

Immunogen: KH-type splicing regulatory protein

Synonyms: FBP2, FUBP2, FUSE binding protein 2, KHSRP, KSRP, p75

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human testis using FNab04525(KHSRP antibody) at dilution of 1:50

Image 2: Immunofluorescent analysis of HeLa cells using FNab04525(KHSRP antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L).

Image 3:

Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab04525(KHSRP antibody) at dilution of 1:500

Gene ID: 8570

Research Area: Metabolism

Uniprot ID: Q92945