anti- LDLR antibody

Product Description

anti- LDLR antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family and is involved in receptor-mediated endocytosis of specific ligands. The LDLR is a cell surface glycoprotein that scavenges LDL from the blood and regulates plasma LDL cholesterol. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits, which promotes the rapid endocytosis of bound LDL. The protein is highly glycosylated through N- and O-linkages and thus migrates at 100 to 160 kDa bands on SDS-PAGE..

Immunogen: low density lipoprotein receptor

Synonyms: FH, FHC, LDL receptor, LDLR

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IP, IF, FC

Recommended dilution: WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human brain tissue slide using FNab04742(LDLR Antibody) at dilution of 1:200 heat mediated antigen retrieved with Sodium Citrate buffer(pH6).

Image 2: Immunofluorescent analysis of ( -20? Ethanol ) fixed HeLa cells using FNab04742 (LDLR antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L).

Image 3:

Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab04742(LDLR antibody) at dilution of 1:300

Gene ID: 3949

Research Area: Metabolism

Uniprot ID: P01130