Product Description
anti- leptin antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Leptin is a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. Leptin is the most critical hormone in the homeostatic regulation of energy balance among those so far discovered. Leptin primarily acts on the neurons of the mediobasal part of hypothalamus to regulate food intake, thermogenesis, and the blood glucose level. Leptin also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. Leptin has also been linked to type 2 diabetes mellitus development..
Immunogen: leptin
Synonyms: FLJ94114, LEP, leptin, OB, Obese protein, Obesity factor, OBS
Reactivity: Human, Mouse
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500
Image 1: Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab04754(LEP Antibody) at dilution of 1:50
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Image 4: human adipose tissue were subjected to SDS PAGE followed by western blot with FNab04754(LEP antibody) at dilution of 1:500
Research Area: Metabolism
Uniprot ID: P41159