anti- LMP2 antibody

Product Description

anti- LMP2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit..

Immunogen: proteasome(prosome, macropain) subunit, beta type, 9(large multifunctional peptidase 2)

Synonyms: 20S proteasome, beta1i, LMP2, Low molecular mass protein 2, Macropain chain 7, Proteasome chain 7, Proteasome subunit beta 1i, Proteasome subunit beta type 9, PSMB6i, PSMB9, RING12

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IP, IF

Recommended dilution: WB: 1:500-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human tonsillitis using FNab04810(PSMB9 antibody) at dilution of 1:50

Image 2: Immunofluorescent analysis of ( 10% Formaldehyde ) fixed MCF-7 cells using FNab04810 (LMP2 antibody) at dilution of 1:50 and Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L).

Image 3:

Image 4: Raji cells were subjected to SDS PAGE followed by western blot with FNab04810(PSMB9 antibody) at dilution of 1:500

Gene ID: 5698

Research Area: Metabolism

Uniprot ID: P28065