Product Description
anti- MAFB antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Acts as a transcriptional activator or repressor. Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, osteoclast, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter(By similarity). Involved either as an oncogene or as a tumor suppressor, depending on the cell context..
Immunogen: v-maf musculoaponeurotic fibrosarcoma oncogene homolog B(avian)
Synonyms: KRML
Reactivity: Human, Rat
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: RAW 264.7 cells were subjected to SDS PAGE followed by western blot with FNab04930( MAFB Antibody) at dilution of 1:1000
Gene ID: 9935
Research Area: Metabolism
Uniprot ID: Q9Y5Q3