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Product Description
anti- MBD2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters..
Immunogen: methyl-CpG binding domain protein 2
Synonyms:
Reactivity: Human, Rat
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab05034(MBD2 antibody) at dilution of 1:1000
Gene ID: 8932
Research Area: Metabolism
Uniprot ID: Q9UBB5
