Product Description
anti- MBD3 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself(PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides(in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides(PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases..
Immunogen: methyl-CpG binding domain protein 3
Synonyms:
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF, IP
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human endometrial cancer using FNab05035(MBD3 antibody) at dilution of 1:100
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Image 4: Y79 cells were subjected to SDS PAGE followed by western blot with FNab05035(MBD3 antibody) at dilution of 1:600
Gene ID: 53615
Research Area: Metabolism
Uniprot ID: O95983