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Product Description
anti- MCM7 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Acts as component of the MCM2-7 complex(MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage..
Immunogen: minichromosome maintenance complex component 7
Synonyms: CDC47, MCM2
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IP, IHC
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab05062(MCM7 Antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab05062(MCM7 Antibody) at dilution of 1:3000
Gene ID: 4176
Research Area: Metabolism
Uniprot ID: P33993
