Product Description
anti- MED8 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins..
Immunogen: mediator complex subunit 8
Synonyms:
Reactivity: Human, Mouse
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: HepG2 cells were subjected to SDS PAGE followed by western blot with FNab05099(MED8 antibody) at dilution of 1:1000
Gene ID: 112950
Research Area: Metabolism
Uniprot ID: Q96G25