anti- MEF2C antibody

Product Description

anti- MEF2C antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture(By similarity). Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2..

Immunogen: myocyte enhancer factor 2C

Synonyms:

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human brain using FNab05106(MEF2C antibody) at dilution of 1:50

Image 2: .

Image 3:

Image 4: mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with FNab05106(MEF2C antibody) at dilution of 1:300

Gene ID: 4208

Research Area: Metabolism

Uniprot ID: Q06413