anti- MEK5 antibody

Product Description

anti- MEK5 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms(aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described..

Immunogen: mitogen-activated protein kinase kinase 5

Synonyms: HsT17454, MAP kinase kinase 5, MAP2K5, MAPK/ERK kinase 5, MAPKK 5, MAPKK5, MEK 5, MEK5, MKK5, PRKMK5

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:100

Image 1: Immunohistochemistry of paraffin-embedded human heart using FNab05117(MAP2K5 antibody) at dilution of 1:50

Image 2: Immunofluorescent analysis of U2OS cells, using MAP2K5 antibody FNab05117 at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red)..

Image 3:

Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab05117(MAP2K5 antibody) at dilution of 1:500

Gene ID: 5607

Research Area: Metabolism

Uniprot ID: Q13163