anti- MIA3 antibody

Product Description

anti- MIA3 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII(COL7A1) secretion by loading COL7A1 into transport carriers. It may participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. It is also specifically required for the secretion of lipoproteins by participating in their export from the endoplasmic reticulum(PubMed:27138255)..

Immunogen: melanoma inhibitory activity family, member 3

Synonyms: KIAA0268, TANGO, TANGO1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IP, WB

Recommended dilution:

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Image 4: HEK-293T cells were subjected to SDS PAGE followed by western blot with FNab05174(MIA3 antibody) at dilution of 1:500

Gene ID: 375056

Research Area: Metabolism

Uniprot ID: Q5JRA6