anti- MITF antibody

Product Description

anti- MITF antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences(E-boxes)(5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase(TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase(TYR) and tyrosinase-related protein 1(TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium..

Immunogen: microphthalmia-associated transcription factor

Synonyms: bHLHe32, MI, MITF, WS2A

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, FC, IP

Recommended dilution: WB: 1:1000-1:10000; IP: 1:500-1:5000

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Image 3: IP Result of anti-MITF (IP: FNab05198, 4ug; Detection: FNab05198 1:1000) with mouse heart tissue lysate 4000ug.

Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab05198(MITF antibody) at dilution of 1:400

Gene ID: 4286

Research Area: Metabolism

Uniprot ID: O75030