anti- MMACHC antibody

Product Description

anti- MMACHC antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Catalyzes the reductive dealkylation of cyanocobalamin to cob(II)alamin, using FAD or FMN as cofactor and NADPH as cosubstrate(PubMed:19700356, PubMed:21697092, PubMed:22642810). Can also catalyze the glutathione-dependent reductive demethylation of methylcobalamin, and, with much lower efficiency, the glutathione-dependent reductive demethylation of adenosylcobalamin(PubMed:19801555, PubMed:22642810, PubMed:25809485). Under anaerobic conditions cob(I)alamin is the first product; it is highly reactive and is converted to aquocob(II)alamin in the presence of oxygen(PubMed:19801555). Binds cyanocobalamin, adenosylcobalamin, methylcobalamin and other, related vitamin B12 derivatives(PubMed:21071249)..

Immunogen: methylmalonic aciduria(cobalamin deficiency) cblC type, with homocystinuria

Synonyms:

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB

Recommended dilution:

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Image 4: Raji cells were subjected to SDS PAGE followed by western blot with FNab05227( MMACHC Antibody) at dilution of 1:600

Gene ID: 25974

Research Area: Metabolism

Uniprot ID: Q9Y4U1