anti- MYL2 antibody

Product Description

anti- MYL2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Contractile protein that plays a role in heart development and function(By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force(By similarity). During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly(By similarity)..

Immunogen: myosin, light chain 2, regulatory, cardiac, slow

Synonyms: MLC2

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, WB

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human heart tissue slide using FNab05486(MYL2 Antibody) at dilution of 1:50

Image 2: .

Image 3:

Image 4: rat heart tissue were subjected to SDS PAGE followed by western blot with FNab05486(MYL2 Antibody) at dilution of 1:5000

Gene ID: 4633

Research Area: Metabolism

Uniprot ID: P10916