anti- MYO7A antibody

Product Description

anti- MYO7A antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial(RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity(By similarity). Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing..

Immunogen: myosin VIIA

Synonyms: USH1B

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IF

Recommended dilution:

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Image 4: L02 cells were subjected to SDS PAGE followed by western blot with FNab05507(MYO7A antibody) at dilution of 1:500

Gene ID: 4647

Research Area: Metabolism

Uniprot ID: Q13402