anti- NAT10 antibody

Product Description

anti- NAT10 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs(PubMed:25653167). Catalyzes the formation of N(4)-acetylcytidine(ac4C) at positions 1337 and 1842 in 18S rRNA(By similarity). Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis(PubMed:25653167). Catalyzes the formation of ac4C in serine and leucine tRNAs(By similarity). Requires the tRNA-binding adapter protein THUMBD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation(PubMed:25653167). Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division(PubMed:14592445, PubMed:17631499, PubMed:18082603, PubMed:19303003)..

Immunogen: N-acetyltransferase 10(GCN5-related)

Synonyms: ALP, KIAA1709

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IF, IP

Recommended dilution:

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab05562( NAT10 Antibody) at dilution of 1:3000

Gene ID: 55226

Research Area: Metabolism

Uniprot ID: Q9H0A0