anti- NCK1 antibody

Product Description

anti- NCK1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. Modulates the activation of EIF2AK2/PKR by dsRNA. May play a role in cell adhesion and migration through interaction with ephrin receptors..

Immunogen: NCK adaptor protein 1

Synonyms: NCK

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF, FC, IP

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer using FNab05583(NCK1 antibody) at dilution of 1:100

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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab05583(NCK1 antibody) at dilution of 1:400

Gene ID: 4690

Research Area: Metabolism

Uniprot ID: P16333