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Product Description
anti- NEDD4L antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene..
Immunogen: neural precursor cell expressed, developmentally down-regulated 4-like
Synonyms: KIAA0439, NEDL3
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Image 1: Immunohistochemistry of paraffin-embedded human prostate using FNab05646(NEDD4L antibody) at dilution of 1:200
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Image 4: K-562 cells were subjected to SDS PAGE followed by western blot with FNab05646(NEDD4L antibody) at dilution of 1:1000
Gene ID: 23327
Research Area: Metabolism
Uniprot ID: Q96PU5
